What risk factor is related to Paget-Schroetter syndrome?

Paget-Schroetter syndrome, also known as effort thrombosis, is primarily associated with thrombosis occurring in the thoracic outlet region, often involving the subclavian vein. One of the key risk factors for this syndrome is trauma. This can include repetitive overhead motion and acute injuries that lead to vascular compression or irritation, particularly in athletes or individuals engaged in activities that require significant upper extremity movement.

While genetic predisposition, obesity, and diabetes mellitus are known to contribute to other vascular conditions, they are not the primary causes associated with Paget-Schroetter syndrome. Trauma leading to thrombosis in the venous system is a direct contributor to the etiology of the syndrome, highlighting the importance of understanding the relationship between physical strain and vascular health in this context.